Aspartame kye kimu ku bikozesebwa mu kugatta emmere ebisinga okunoonyezebwa obulungi mu nsi yonna. Ng’ekiwoomerera eky’obutonde eky’amaanyi amangi, kiwa obuwoomi obuyonjo, obulinga ssukaali-nga buwooma emirundi nga 200 okusinga obuwoomi bwa sucrose, naye kumpi tebukola kalori yonna. Olw’ensonga eno, kifuuse ekirungo ekikulu mu nkumi n’enkumi z’ebintu ebikendedde-kalori ne ssukaali-ebitaliimu, okuva ku byokunywa ebikalu ebirimu kaboni, ebyokunywa ebirimu butto, ne ggaamu okutuuka ku yogati, ice cream, ssweeta, ne kaawa ow’amangu. Ku mugabi yenna ow’obuvunaanyizibwa aspartame, okukakasa nti bakasitoma bategeera bulungi byombi emigaso gy’emirimu n’ebyetaago ebikakatako eby’okuwandiika ekirungo kino si nsonga ya kugoberera mateeka gokka-kiba kwewaayo eri obwerufu, obukuumi bw’abakozesa, n’ebyobulamu by’abantu bonna.
Okusinziira ku mutindo gw'eggwanga lya China *GB 2760-2014 – National Food Safety Standard for Uses of Food Additives*, emmere yonna erimu aspartame erina okugilangirira obulungi ku lukalala lw'ebirungo nga "Aspartame (erimu phenylalanine)." Okwetaaga kuno si kwa kimpowooze, era si kwa njawulo mu China. Mu butuufu, ebiragiro ebifaanagana eby’okuwandiika ebiwandiiko biriwo mu mukago gwa Bulaaya (wansi w’etteeka (EC) No 1333/2008), Amerika (nga bayita mu mateeka ga FDA agakwata ku kuwandiika emmere), n’ebitundu ebirala bingi mu nsi yonna. Obutuufu bw’etteeka lino eri abantu bonna bulaga okukkaanya okumanyiddwa mu nsi yonna mu bya ssaayansi n’eby’obusawo.
Okutegeera lwaki akabonero kano akagere keetaagibwa, omuntu alina okusooka okutegeera ekituuka ku aspartame oluvannyuma lw’okuginywa. Bw’omira, aspartame emenyekamenyeka mangu era mu bujjuvu mu nkola y’olubuto lw’omuntu olw’esterases ne peptidases mu bitundu bisatu ebisookerwako ebikyusa ebiriisa: phenylalanine (nga 50% ku buzito), aspartic acid (nga 40%), ne methanol omutono (nga 10%). Ebirungo bino ebikyusa ebiriisa bitera okusangibwa mu bungi obw’amaanyi ennyo mu mmere nnyingi eza bulijjo. Okugeza, egiraasi y’amata erimu ekirungo kya phenylalanine ne aspartic acid bingi okusinga ekibbo kya sooda ow’emmere awoomeddwa ne aspartame. Ekirala, okunoonyereza kwa ssaayansi okunene-nga mw’otwalidde n’okunoonyereza okungi okw’ekiseera ekiwanvu-ku bantu-kukakasizza nti ne ku mutindo omungi ogw’okunywa ogwa 200 mg buli kkiro y’obuzito bw’omubiri buli lunaku, tewali aspartame azuuliddwa ataliiko kamogo ayingira mu musaayi. Mu ngeri endala, aspartame akyusibwamu ddala, takuŋŋaanyizibwa mu mubiri, era terina bulabe bwonna eri abantu abasinga obungi.
Wabula ku kibinja ekitono eky’abantu ssekinnoomu, phenylalanine ya bulabe bwa maanyi. Abantu bano balina obuzibu obutatera kulabika obusikira mu nkyukakyuka y’emmere obumanyiddwa nga phenylketonuria (PKU). PKU mbeera ya autosomal recessive ereetebwa obutaba na enzyme phenylalanine hydroxylase, evunaanyizibwa ku kukyusa phenylalanine okufuuka tyrosine. Awatali nkola emala ya enzyme eno, phenylalanine ekuŋŋaanyizibwa okutuuka ku butwa mu musaayi n’ebitundu by’omubiri. Singa tekuddukanyizibwa, okuzimba kuno kuleetera obusimu okwonooneka okw’amaanyi era okutasobola kuddamu, omuli okulemererwa mu magezi, okulwawo okukula, obuzibu mu nneeyisa, okukonziba, ate mu mbeera ezimu, okwonooneka kw’obwongo okw’olubeerera.
PKU ekosa abalongo nga 1 ku buli 10,000 ku 1 ku 20,000 mu nsi yonna, wadde ng’obungi bwayo bwawukana okusinziira ku bungi bw’abantu. Ku bantu bano ssekinnoomu, okukugira ennyo emmere ey’obulamu bwonna ku phenylalanine si kya kwesalirawo-kyetaagisa mu by’obujjanjabi. Olw’okuba aspartame nsibuko ya maanyi ya phenylalanine bw’enywa mu bintu ebingi olunaku lwonna, abalwadde ba PKU n’abalabirira balina okusobola okugizuula n’okugyewala amangu ddala. Ekiwandiiko "Aspartame (kirimu phenylalanine)" kikola ekigendererwa kino kyennyini. Kye kulabula obutereevu, okutaliimu kubuusabuusa okusobozesa abantu ssekinnoomu abalina PKU okulonda emmere etali ya bulabe nga tebalina kutaputa mannya ga ddagala oba okuteebereza oba ekintu ekiweereddwa kiyinza okuba eky’obulabe.
Okusinziira ku ndowooza y’omugabi wa aspartame ow’obuvunaanyizibwa, okugoberera etteeka lino ery’okuwandiika ebiwandiiko kiraga emisingi emikulu egiwerako. Ekisooka, kiraga okugoberera ennyo amateeka g’eggwanga n’ensi yonna agakwata ku by’okwerinda by’emmere. Ekyokubiri, kiraga okutegeera okw’amaanyi ku ssaayansi ali emabega w’ekirungo ekyo, omuli n’enkyukakyuka yaakyo n’omuwendo gwakyo ogw’enjawulo ogulina okukyewala. Ekyokusatu, era ekisinga obukulu, kitegeeza okwewaayo okukuuma abaguzi abali mu bulabe. Okussaamu ekigambo "kirimu phenylalanine" si kiraga nti aspartame si nnungi eri abantu bonna-okunoonyereza okw'emyaka mingi okuzingiramu ebikumi n'ebikumi by'okunoonyereza bulijjo kuzzeemu okukakasa obukuumi bwayo eri abantu bonna, omuli abakyala ab'embuto, abaana, n'abantu abalina ssukaali. Wabula, kye kikuuma ekigendereddwamu eri ekibinja ekitono, ekitali kinywevu mu by’obujjanjabi.
Okugatta ku ekyo, ekyetaagisa kino eky’okuwandiika ebigambo kiyamba okuziyiza amawulire amakyamu. Awatali kabonero akategeerekeka obulungi, akatuufu, abaguzi bayinza okusanga ebigambo ebitali bitegeerekeka oba ebibuzaabuza ebikwata ku aspartame ku yintaneeti oba mu mikutu gy’amawulire. Nga balagira okulangirira okutuufu, okwesigamiziddwa ku ssaayansi-, abalungamya bakakasa nti amawulire agatuuka ku bakozesa gakwatagana, matuufu, era gasobola okukolebwako. Ku maka ga PKU, obutuufu obwo buyinza okutegeeza enjawulo wakati w’okukuuma obulamu n’okufuna obulabe obutakyuka.
Mu kumaliriza, obwetaavu bw'okuwandiika aspartame nga "Aspartame (alimu phenylalanine)" kyakulabirako kya mulembe eky'okulungamya emmere okwesigamiziddwa ku bujulizi-. Kikuuma ebyobulamu by’abantu awatali kussa migugu egiteetaagisa ku mulimu gw’emmere oba okutiisa abantu bonna. Nga omugabi wa aspartame ow’obuvunaanyizibwa, tuwagira mu bujjuvu era tugoberera nnyo ekyetaagisa kino eky’okuwandiika-si lwakuba nti etteeka likiragira, naye kubanga okukuuma buli mukozesa, omuli n’abo abalina embeera z’obujjanjabi ezitatera kubaawo, kye kintu ekituufu okukola. Tukkiriza nti okuwandiika ebiwandiiko mu ngeri entegeerekeka kizimba obwesige, kisobozesa okulonda mu ngeri ey’amagezi, era ku nkomerero kiyamba ku buli muntu okufuna emmere ey’obukuumi, entangaavu.